Holly Lasnetski v. HHS - HPV, sensory nervous system problems and sensory dysesthesia, fatigue, fever, nausea, vomiting, constipation, heartburn, reflux, abdominal pain and cramping, urine frequency issues, rash, memory impairment, muscle weakness, alteration in menstrual pattern, ataxia, flushing, chills and fever, and aggravated back problems (2016)

Holly Lasnetski, born in 1986, received the Gardasil (HPV) vaccine on July 18, 2011. She alleged that she suffered from sensory nervous system problems, sensory dysesthesia, and a wide array of other symptoms, including fatigue, nausea, memory impairment, and pain, which she claimed were caused by the vaccine.

Prior to vaccination, Ms. Lasnetski had a history of various medical complaints, including headaches, tingling, anxiety, and respiratory infections.

Following vaccination, she reported a multitude of symptoms, with some reports indicating onset within hours or days, while others suggested symptoms appeared within a month or nearly a year later. Medical evaluations, including those at the Mayo Clinic, did not yield a definitive diagnosis of a specific injury caused by the vaccine, with some physicians suggesting an 'idiosyncratic severe reaction' or 'immuno-inflammatory tendency' but also noting the absence of permanent autonomic injury or well-defined connective tissue disease.

Petitioner's expert, Dr. Dahlgren, opined that the vaccine caused an adverse autoimmune reaction, while respondent's expert, Dr.

Leist, argued that the alleged conditions were symptoms of an unknown injury and that the temporal relationship was too rapid for causation. The Special Master dismissed the petition, finding that Ms.

Lasnetski had failed to identify a 'defined and recognized injury' as required by the Vaccine Act, and therefore, the question of causation could not be reached. This decision was affirmed on review, as the court found the Special Master's conclusion that the alleged conditions were symptoms rather than defined injuries was not arbitrary or capricious, and thus, the Althen causation analysis was not required.